A plasmonic chip-based bio/chemical hybrid sensing system for the highly sensitive detection of C-reactive protein.
نویسندگان
چکیده
A synthetic polymer ligand-grafted plasmonic chip was fabricated and demonstrated a highly sensitive detection of C-reactive protein (CRP) by grating-coupled surface plasmon field-enhanced fluorescence. Poly(2-methacryloyloxyethyl-phosphorylcholine) was used as a CRP-specific polymer ligand layer and was grafted onto the plasmonic chip using surface-initiated controlled/living radical polymerization (limit of detection: ca. 10 pM).
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ورودعنوان ژورنال:
- Chemical communications
دوره 52 20 شماره
صفحات -
تاریخ انتشار 2016